What percentage of cancers is estimated to be hereditary?

Hereditary cancers are those that result from genetic mutations passed down from parents to their offspring. The estimated percentage of cancers that are attributable to hereditary factors is approximately 5-10%. This means that a significant majority of cancers are considered sporadic or are caused by non-genetic factors. Hereditary cancers are often linked to specific genetic syndromes, such as Lynch syndrome or BRCA mutations, which increase the risk for certain types of cancer, like breast and colorectal cancers.

Understanding the percentage helps in identifying and managing patients who may be at increased risk. If a patient has a family history suggestive of hereditary cancer syndromes, genetic counseling and testing can be recommended to assess their risk. This understanding drives patient education, screening recommendations, and preventive measures. Recognizing the hereditary component in a smaller percentage of cancers emphasizes the importance of a comprehensive family history and potential surveillance strategies for those who carry genetic predispositions.